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Impaired glucose tolerance (IGT)

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Impaired Glucose Tolerance (IGT):Methodist Health:"A person is diagnosed with IGT when the 2-hour glucose results from a glucose tolerance test are greater than 140, but less than 200mg/dl. Discussions among professional agencies, such as the American Diabetes Association and the World Health Organization, are underway to amend this protocol so that mild or early cases can be diagnosed earlier."
http://www.methodisthealth.com/diabetes/igt.htm

What causes IGT and why is it important?:Diabetes in Control:"IGT (and type 2 diabetes) results from a combination of impaired insulin secretion and reduced sensitivity of the body's cells to insulin (insulin resistance). The observation that people with IGT have elevated post-meal blood glucose levels but near-normal fasting blood glucose suggests that the main defect in IGT may be impaired insulin secretion, although insulin resistance is also almost always present."
http://www.diabetesincontrol.com/education/IMPAIRED%20GLUCOSE%20TOLERANCE.htm

Impaired Glucose Tolerance:diabetesnet.com:"An estimated 20 million people have IGT in the U.S. and this number is growing rapidly. 50 percent of the people whom have IGT are most likely to develop Type 2 diabetes, however diet, exercise and superior glucose monitoring can greatly reduce the onset of diabetes altogether."
http://www.diabetesnet.com/diabetes_types/impaired_glucose_tolerance.php

Identifying people with 'Borderline diabetes' can lead to preventing disease and it's complications:Foot.com:"Research shows that people with impaired glucose tolerance or 'borderline diabetes' are at greater risk of developing diabetes, as well as heart disease and other problems we associate with diabetes itself," says Edward S. Horton, M.D., director of clinical research at Joslin Diabetes Center in Boston. "But the results of the nationwide Diabetes Prevention Program issued this summer showed that people with impaired glucose tolerance can reduce their risk of developing diabetes by 58 percent if they lose a modest amount of weight and begin a program of 30 minutes exercise daily"
http://news.foot.com/news/937.html

What you need to know about pre-diabetes:About.com:"Pre-diabetes is nothing new. You may know it by its clinical handles - impaired glucose tolerance (IGT) or impaired fasting glucose (IFG). In layman's terms, it is blood glucose levels that are higher than normal, but not high enough to be diabetes. And as obesity grows to epidemic proportions and lifestyles become more sedentary both in the U.S. and abroad, the pre-diabetes problem has taken on greater urgency.The Surgeon General estimates that 61 percent of U.S. adults are overweight, as are 13 percent of children and adolescents. Being overweight or obese is a primary risk factor for developing pre-diabetes and type 2 diabetes. A body mass index (BMI) of 25 to 29.9 is considered overweight, and a BMI of 30 or higher is obese"
http://diabetes.tqn.com/library/weekly/aaprediabetesa.htm

What is meant by pre-diabetes?:Hope Warshaw Associates:"Pre-diabetes is a new term. It was coined by Secretary of Health and Human Services Tommy Thompson in March '02. Pre-diabetes, more formally called "impaired glucose tolerance" or "impaired fasting glucose", means that your blood glucose is higher than normal, but not high enough to be called diabetes. The numbers are Fasting between 110 - 125 mg/dl and for Random blood glucose between 140 - 199 mg/dl. It is estimated that about 16 million people in the U.S. have pre-diabetes. If you have pre-diabetes you are likely to develop diabetes or diabetes symptoms within 10 years unless you do something about it and you are at greater risk of heart disease and stroke. The message to you is: TAKE ACTION NOW"
http://www.hopewarshaw.com/faqs/diabetesprediabetes.htm

What is IGT and how is it diagnosed?:Joslin Diabetes Center:"How does the fasting blood glucose test differ from the oral glucose tolerance test? In the fasting blood glucose test, a person's blood glucose is measured after a fast of 8 to 12 hours: A person with normal blood glucose has a blood glucose level below 110 A person with impaired fasting glucose has a blood glucose level between 110 and 125 mg/dl. If the fasting blood glucose level rises to126 mg/dl or above, a person has diabetes. The OGTT includes measures of blood glucose levels after a fast and after a glucose challenge. In 1997, an American Diabetes Association (ADA) expert panel recommended that doctors use the fasting blood glucose test to screen their patients for diabetes because the test is easier and less costly than the OGTT. Though the fasting glucose test detects most diabetes cases, the OGTT is more sensitive in identifying people with blood glucose problems that may first appear only after a glucose challenge."
http://www.joslin.harvard.edu/education/library/prevent_itg.shtml

High-risk groups:stop-niddm.com:"The prevalence of IGT and NIDDM increase with age, affecting 42% of those aged 65 to 74 years. The risk of abnormal glucose tolerance is also greatly increased in minority populations including African, Hispanic and Native Americans. Because the proportions of the US population aged over 65, and of the high-risk ethnic and racial groups are increasing, the overall prevalence of NIDDM and IGT in the USA is expected to continue to increase during the next decade"
http://www.stop-niddm.com/igt/prevelance.htm

IGT Significantly Increases the Risk of Cardiovascular Diseases:about.com:"In addition to a high risk of type 2 diabetes, IGT significantly increases the risk of cardiovascular diseases such as heart disease and stroke. Recent research shows that people with IGT are 34% more likely to die from cardiovascular diseases over the next nine years than people with normal blood glucose levels. Furthermore, many people who go on to develop type 2 diabetes already have cardiovascular complications by the time they are diagnosed."
http://diabetes.about.com/library/blnews/blnigt801.htm

An introduction to diabetes, IGT and IFG and eating healthy:Eating 4 Health:"The related conditions of Impaired Glucose Tolerance (IGT) and Impaired Fasting Glycaemia (IFG) occur when individuals have some abnormality of blood glucose levels, but not high enough to give a diagnosis of diabetes. The diagnostic levels for diabetes are defined by the World Health Organisation. People with IGT or IFG have an increased risk of developing diabetes and heart disease. The conditions of type 2 diabetes, IFG and IGT are mainly diagnosed in the over forty age group, but younger people can also be at risk, particularly if they are overweight. As the number of people who are overweight is increasing, so is the incidence of these conditions. Type 2 diabetes can also be inherited."
http://www.eating4health.co.uk/db_guide.html


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Last updated by Andrew Lopez, RN on Wednesday, September 29, 2010


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