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Diabetic Complications

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List and explanation of diabetic complications:Diabetes UK:"Diabetic complications can occur at any age and can vary from patient to patient. Complications generally occur due to poor management of Diabetes. Though we do not wish to scare you this subject must be raised. Complications can be reduced through good control and exercise."
Diabetes UK
10 Parkway
London NW1 7AA.
London Telephone:
020-7424-1000
Fax: 020-7424-1001
http://ourworld.compuserve.com/homepages/BDA_EDDIE_EVANS/page12.htm

A collection of information on the study of complications in diabetes:Center for the study of complications in diabetes:"The Juvenile Diabetes Research Foundation Center for the Study of Complications in Diabetes brings together some of the world's leading diabetes authorities to find new ways to understand and treat three of the most devastating complications of the disease: diabetic neuropathy (progressive nerve damage), diabetic nephropathy (progressive kidney damage), and diabetic retinopathy (progressive damage to the retina). Diabetic neuropathy leads to loss of feeling in the feet and hands, and is the most common cause of "nontraumatic" amputations in the United States (amputations not due to accidents). Diabetic nephropathy is the number one cause of renal failure requiring dialysis in our country. Diabetic retinopathy impairs eyesight and is the nation's leading cause of nontraumatic blindness. The Center is the first JDRF Center to focus exclusively on these three complications of diabetes."
University of Michigan, Department of Neurology
4414 Kresge III, 200 Zina Pitcher Place
Ann Arbor, Michigan 48109
mfunnell@umich.edu
http://www.umich.edu/~jdrf/

Long and short term complications explained:Whinfield Surger UK:"Long-term complications. This is the main reason for holding diabetic clinics. After some controversy a few years ago it is now widely accepted that good diabetic control plus control of blood pressure and cholesterol has a vital role to play in reducing the long term consequences of being diabetic. These are: Eye complications. Diabetes can affect the circulation to the back of the eye. The most serious form of this complication causes the production of fragile new blood vessels which can easily burst causing a haemorrhage which can blind the eye. Kidney complications. Diabetes is a major cause of kidney failure. As with the eye the site of the damage is in the small blood vessels where filtering of impurities takes place. An early sign of damage taking place is the presence of a protein called albumin in the urine. Initially the quantities may be very small so a special test to look for microalbuminuria is done at the laboratory. Circulation problems. Diabetes tends to attack the smaller blood vessels and the feet and toes are particularly vulnerable. At worst this can lead to ulcers that are difficult to heal and even gangrene. Nerve damage: Sensory nerves. Loss of sensation again tends to involve the feet. Autonomic nerves. These nerves control such things as blood pressure and male potency.Heart disease. There is an increased rate of angina and heart attack in diabetics."
http://www.whinfield.co.uk/Page7.html

Charts listing complications, cause, signs and prevention of diabetic complications:Diabetes and You:"The primary concern for people with diabetes has always been to avoid both acute and chronic complications. For people with diabetes, it is important to understand the risk of complications the disease can cause. With this knowledge, one is better equipped to make important decisions to maintain good health."
http://www.sokkari.com/complications.htm

Comprehensive list and explanation of complications of diabetes:Holisticonline.com:"Hyperosmolar nonketogenic coma This is usually the result of profound dehydration as a result of not taking enough fluids or due to fluid loss from events such as pneumonia, burns, stroke, a recent operation, or certain drugs such as phenytoin, diazoxide, glucocorticoids and diuretics. With a death rate of over 50 per cent, this is a true medical emergency. Prompt medical attention is warranted to save life. The condition may develop over a period of days or weeks. The diabetic patient's condition is worsened by the appearance of six major complications of diabetes.Diabetic retinopathy Diabetic neuropathy Diabetic nephropathy Diabetic foot ulcers Glycosylated proteins Aldose reductase"
info@holisticonline.com
http://www.holistic-online.com/Remedies/Diabetes/diabetes_complications.htm

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Information about numerous diabetic complications by catagory:NIH Publication No. 97-241:"How diabetes causes long-term problems is unclear. However, changes in the small blood vessels and nerves are common. These changes may be the first step toward many problems that diabetes causes. Scientists can't predict who among people with diabetes will develop complications, but complications are most likely to occur in someone who has had diabetes for many years. However, because a person can have diabetes without knowing it, a complication may be the first sign.Diabetes can cause long-term complications such as heart, kidney, eye, and nerve disease."
Office of Communications and Public Liaison
NIDDK, NIH, Building 31
Room 9A04
31 Center Drive, MSC 2560
Bethesda, MD 20892-2560, USA
Contact NIDDK
http://www.niddk.nih.gov/health/diabetes/pubs/niddm/compl.htm

chart of tests, exams and what to talk to your doctor about:Green & Seidner Family Practice Associates Online:"If you are diabetic, we recommend that you follow the following guidelines for the management of your condition"
PO Box 1278
826 N. Broad St.
Lansdale, PA 19446
215-855-1054
greenandseidner@hotmail.com
http://www.greenandseidner.com/diabetes.html

Quick Reference guild to screening and management of complications:waukeshafp.org:"Osteomyelitis should be suspected whenever the ulcer covers more than 2 cm2 with a depth more than 3 mm or if any bone is exposed or is felt with probing. It should also be suspected if an apparently healed ulcer keeps breaking back down. When osteomyelitis is suspected then consider use of plain films to look for soft tissue gas and bone involvement to help confirm the diagnosis although the latter requires 2-4 weeks to develop. For increased sensitivity technetium diphosponate bone scans can be used to show increased osteoblast activity and are often combined with either gallium 67 scans or indium-labeled scintigraphy which show increased granulocyte activity. Unfortunately, with these scans it may be difficult to differentiate the overlying inflammation of a soft tissue ulcer from osteomyelitis; however, it can have a diagnostic accuracy of 89% for hind and mid-foot infections. MRI's can detect the bone edema of osteomyelitis earlier than plain radiographs; however, this may be hard to differentiate from non-specific reactive marrow edema due to overlying soft tissue ulcers. Thus specificity can be as low as 75% although it may help to determine the presence of soft tissue abscesses and is particularly helpful for forefoot lesions."
http://www.waukeshafp.org/DMExam.html

Good Sugar Control Results in Few Diabetic Complications For Type 1 Diabetics:Doctor's Guide Publishing Limited:"People with diabetes who intensively manage their blood sugar experience long-lasting benefits, researchers have found. For people with type 1 diabetes who participated in the Diabetes Control and Complications Trial (DCCT), the benefits of intensive blood sugar control at reducing diabetic complications persisted for four years after the trial ended. These were the findings of a DCCT follow-up study, called Epidemiology of Diabetes Interventions and Complications (EDIC), published Feb. 10 in The New England Journal of Medicine. The striking new finding is that people who received intensive therapy during DCCT continued to have a lower risk of eye and kidney disease than those who had been on conventional treatment, even though both groups' HbA1c values leveled off at about 8 percent during 1994 to 1998, the first four years of EDIC"
contact Doc's Guide
http://www.pslgroup.com/dg/16328e.htm

Improving glucose control can lead to better control over diabetic complications:The McGraw-Hill Companies:"The landmark Diabetes Control and Complications Trial proved that hyperglycemia is directly related to development of diabetic microvascular complications and that glucose control can reduce or even prevent retinopathy, neuropathy, and nephropathy. These findings have profound implications in prevention and care of foot ulcers, a common complication of diabetes. In this article, Dr Culleton summarizes how to help patients become part of a healthcare team working to avoid possible serious consequences of uncontrolled hyperglycemia.Foot ulcers and amputation are common complications of diabetes mellitus. Improving glucose control and educating patients in routine care of their feet can reduce the incidence of diabetic foot complications. A multidisciplinary healthcare team including physicians, podiatrists, diabetes educators, and nurses provides an effective comprehensive approach to care of diabetic patients."
http://www.postgradmed.com/issues/1999/07_99/culleton.htm

What is your role in preventing complications:Prevent Blindness America:"Research has shown that people with diabetes must play a more active role in reducing vision loss and other complications from the disease, such as kidney disease, stroke and nerve damage. The results from a major NIH-supported clinical study, called the Diabetes Control and Complications Trial, showed that people with diabetes who keep their blood sugar levels as normal as possible will slow the onset and progression of diabetic retinopathy and help maintain good, healthy vision. A free brochure on diabetic retinopathy is available by calling 1-800-331-2020."
For more information:
Alice Kelsey
1-800-331-2020
AKelsey@preventblindness.org
http://www.preventblindness.org/news/releases/diabetes2_1198.html

C-peptide Reduces Diabetic Complications:Personal MD:"C-peptide, a chain of amino acids created as a by-product of insulin synthesis, appears to prevent or reverse vascular and nerve damage in diabetic rats, according to a study published in the journal Science. "These observations certainly raise the possibility that (C-peptide) might be useful clinically in preventing the onset and even reversing some of the (diabetic) complications in vessels and nerves," said Dr. Joseph Williamson, professor of pathology at Washington University School of Medicine in St. Louis, and lead researcher of the study. Insulin is first synthesized in certain cells of the pancreas as one long polypeptide (chain of amino acids), called proinsulin. After proinsulin achieves a specific shape, or conformation, it is cleaved at precise points to release the active form of insulin -- and C-peptide."
PersonalMD.com
4725 First Street
Suite #275
Pleasanton, CA 94566 , USA
Phone : (925) 417-6840
http://www.personalmd.com/news/a1997072407.shtml

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Amputation:
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Associations:
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Atherosclerosis:
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Backpacking and Diabetes:
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Camps For Diabetic Kids, Children With Diabetes:
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Canine Diabetes:
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Cataracts:
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Cause of Diabetes:
http://www.nursingdiabetics.com/cause/

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Charcot Foot:
http://www.nursingdiabetics.com/charcot/

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Classification of Diabetes:
http://www.nursingdiabetics.com/class/

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Clinical Trials:
http://www.nursingdiabetics.com/trials/

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Complications of Diabetes:
http://www.nursingdiabetics.com/complications/

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Diagnosing diabetes:
http://www.nursingdiabetics.com/diagnosis/

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Dialysis and diabetes:
http://www.nursingdiabetics.com/dialysis/

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Diet for the diabetic:
http://www.nursingdiabetics.com/diet/

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Dyslipidemia:
http://www.nursingdiabetics.com/dyslipidemia/

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Educator (Diabetic Educator):
http://www.nursingdiabetics.com/educator/

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Eye (Diabetic Eye Disease):
http://www.nursingdiabetics.com/eyedisease/

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Feline diabetes:
http://www.nursingdiabetics.com/feline/

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Gestational diabetes:
http://www.nursingdiabetics.com/gestation/

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Glaucoma:
http://www.nursingdiabetics.com/glaucoma/

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Hyperglycemia:
http://www.nursingdiabetics.com/hyperglycemia/

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Hypoglycemia:
http://www.nursingdiabetics.com/hypoglycemia/

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IGT (Impaired glucose tolerance):
http://www.nursingdiabetics.com/IGT/

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Insipidus (diabetes insipidus):
http://www.nursingdiabetics.com/insipidus/

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Ketoacidosis (diabetic ketoacidosis):
http://www.nursingdiabetics.com/keto/

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Kidney Transplant:
http://www.nursingdiabetics.com/transplant/

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Kids and diabetes:
http://www.nursingdiabetics.com/kids/

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Management of diabetes:
http://www.nursingdiabetics.com/management/

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Men and diabetes:
http://www.nursingdiabetics.com/men/

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Nephropathy:
http://www.nursingdiabetics.com/nephropathy/

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Neuropathy:
http://www.nursingdiabetics.com/neuropathy/

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Prevention of diabetes:
http://www.nursingdiabetics.com/prevention/

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Research:
http://www.nursingdiabetics.com/research/

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Retinopathy:
http://www.nursingdiabetics.com/retinopathy/

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Symptoms of diabetes:
http://www.nursingdiabetics.com/symptoms/

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Traveling and diabetes:
http://www.nursingdiabetics.com/traveling/

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Treatment of Diabetes:
http://www.nursingdiabetics.com/diabetestx/

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Type 1 diabetes/ IDDM:
http://www.nursingdiabetics.com/type1/

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Type 2 diabetes/ NIDDM:
http://www.nursingdiabetics.com/type2/

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Ulcer (diabetic ulcer):
http://www.nursingdiabetics.com/ulcer/

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Women and diabetes:
http://www.nursingdiabetics.com/women/

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Diabetic Medications:
http://www.nursingdiabetics.com/medications/

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Last updated by Andrew Lopez, RN on Wednesday, September 29, 2010


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