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Cause of Diabetes

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Cause of type-I diabetes found, researchers say:cnn.com:"Researchers said Monday they had confirmed that type-I diabetes is triggered by the body's immune system turning on delicate cells, and they said they had found the cause. The findings could lead to a type of vaccine against the disease that affects more than 1 million Americans, said Susan Wong and colleagues at Yale University School of Medicine"
http://www.cnn.com/HEALTH/9908/30/health.diabetes.reut/index.html

Common Class of Viruses Implicated as Cause of Type 1 Diabetes:www.diabetes123.com:"Researchers in California and Florida have strong new evidence implicating a common class of viruses in causing Type 1 or insulin-dependent diabetes, a discovery that eventually could lead to ways of preventing the disease that affects as many as 1 million Americans. Type 1 diabetes occurs when the body's immune system attacks and destroys insulin-producing cells in the pancreas. Researchers know that only people with a specific genetic profile are susceptible to this autoimmune attack, but there has been debate about the identity of the agent that triggers the immune reaction. Now, two studies in this month's issues of the Journal of Experimental Medicine and the Journal of Clinical Investigation strongly implicate coxsackie viruses, polio-related viruses that cause upper respiratory infections. One report shows that coxsackie viruses trigger diabetes in genetically susceptible mice but not in those that have a different genetic profile. The second demonstrates that the autoimmune reaction is triggered by a similarity between a coxsackie virus protein and a protein in the pancreas."
http://www.diabetes123.com/d_0n_120.htm

Early-Onset Type 1 Diabetes Has Different Cause Than Later Childhood Onset:docguide:"While the increase in the incidence of type 1 diabetes is most pronounced among children under five years of age, the demographics and autoimmune markers in this age group are poorly characterised. However, researchers from Loma Linda University Children's Hospital, CA, USA, recently identified several factors in patients who develop the disease as babies or toddlers that might suggest a different mechanism to that responsible in older children. The authors compared 47 children who were diagnosed as suffering from type 1 diabetes before five years of age with a representative cohort of 49 children diagnosed after the age of five years. Compared to those diagnosed after the age of five years, children with early-onset diabetes had higher incidence of symptoms of viral illnesses and diabetic ketoacidosis at diagnosis."
http://www.docguide.com/news/content.nsf/news/26A0B4B23BEC4CE8852569E00050F646?OpenDocument&id=48DDE4A73E09A969852568880078C249&c=Diabetes&count=10

Type 1 Diabetes Cause:cssvc.health:"Type 1 diabetes develops as the result of an autoimmune response. An autoimmune response is an abnormal condition in which the body does not recognize some of its own cells and destroys them. In type 1 diabetes, the cells that make insulin.... Type 2 diabetes is caused by a combination of the following two factors: The body tissues do not respond properly to insulin, making it more difficult for the cells to use sugar (glucose) for energy. Body tissues are said to be resistant to insulin or to have insulin resistance. Insulin resistance may cause the pancreas to release excessive amounts of insulin"
http://cssvc.health.webmd.compuserve.com/encyclopedia/article/1667.53148

The Cause of Diabetes:islet.org:"In order to understand a potential cure for diabetes, it is necessary to look briefly at the cause. In insulin-dependent diabetes, the diabetic's body fails to make insulin, a hormone essential to the metabolism of glucose. Glucose enters the blood stream from the food that we eat and, in the presence of insulin, is taken up and "burned" by cells that require this essential fuel. In the absence of insulin, however, glucose accumulates in the blood causing the condition known as high blood sugar (hyperglycemia), while the cells starve for fuel. Without taking insulin injections, the diabetic will slowly starve to death despite abnormally high blood sugar levels."
http://www.islet.org/3.htm

Genes Can Cause Type 2 Diabetes:genetichealth.com:"If you or someone in your family has Type 2 diabetes, you may wonder if other family members are at risk. It turns out that Type 2 diabetes often runs in families and is also more common in some ethnic groups. In fact, researchers have found many genes that can effect your heritable risk for developing Type 2 diabetes. Although researchers know from studying family histories that you can inherit a risk for Type 2 diabetes, they have had difficulty identifying specific gene mutations that cause the disease."
http://www.genetichealth.com/DBTS_Genetics_of_Type_2_Diabetes.shtml

Depression May Cause Diabetes:applesforhealth.com:"Depression, which is common among people with diabetes, may actually cause the disease in some people, researchers are reporting at a major diabetes meeting. Among members of a managed care group in Portland, the 1,680 people who developed diabetes in 1998 were slightly more likely to have experienced depression in the past than people who were matched for age and time of enrollment in the managed care plan but did not develop diabetes, said Gregory A. Nichols of the Kaiser Permanente Center for Health Research in Portland."
http://www.applesforhealth.com/depressdiab2.html

LACK OF VITAMIN D MAY CAUSE JUVENILE DIABETES:drmirkin.com:"A study in the British medical journal, Lancet, reports that lack of vitamin D may cause juvenile diabetes. If that is true, lack of vitamin D may also cause some cases of lupus, and Crohn's disease. The beta cells of your pancreas produce insulin and release it into your bloodstream when your blood sugar starts to rise. Juvenile diabetes is caused by a person's immunity not doing its job of killing germs. Instead, the white blood cells attack the beta cells in the pancreas and destroy them so they can't produce insulin. Then, lack of insulin causes blood sugar levels to rise too high and the person develops diabetes. One hundred years ago, tuberculosis was treated by exposing skin to sunshine. During the industrial revolution, many people worked 18 hours a day and were never out in the sunshine. When these people developed tuberculosis they were sent off to sanitoriums where they sat in the sun and ate good food, and many got better. Let's see if this clue can help to work out the puzzle of what causes juvenile diabetes"
http://www.drmirkin.com/diabetes/9570.html



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Cause of Diabetes:
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Charcot Foot:
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Complications of Diabetes:
http://www.nursingdiabetics.com/complications/

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Diagnosing diabetes:
http://www.nursingdiabetics.com/diagnosis/

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Dialysis and diabetes:
http://www.nursingdiabetics.com/dialysis/

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Diet for the diabetic:
http://www.nursingdiabetics.com/diet/

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Dyslipidemia:
http://www.nursingdiabetics.com/dyslipidemia/

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Educator (Diabetic Educator):
http://www.nursingdiabetics.com/educator/

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Eye (Diabetic Eye Disease):
http://www.nursingdiabetics.com/eyedisease/

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Feline diabetes:
http://www.nursingdiabetics.com/feline/

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Gestational diabetes:
http://www.nursingdiabetics.com/gestation/

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Glaucoma:
http://www.nursingdiabetics.com/glaucoma/

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Hyperglycemia:
http://www.nursingdiabetics.com/hyperglycemia/

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Hypoglycemia:
http://www.nursingdiabetics.com/hypoglycemia/

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IGT (Impaired glucose tolerance):
http://www.nursingdiabetics.com/IGT/

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Insipidus (diabetes insipidus):
http://www.nursingdiabetics.com/insipidus/

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Ketoacidosis (diabetic ketoacidosis):
http://www.nursingdiabetics.com/keto/

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Kidney Transplant:
http://www.nursingdiabetics.com/transplant/

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Kids and diabetes:
http://www.nursingdiabetics.com/kids/

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Management of diabetes:
http://www.nursingdiabetics.com/management/

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Men and diabetes:
http://www.nursingdiabetics.com/men/

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Nephropathy:
http://www.nursingdiabetics.com/nephropathy/

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Neuropathy:
http://www.nursingdiabetics.com/neuropathy/

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Prevention of diabetes:
http://www.nursingdiabetics.com/prevention/

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Research:
http://www.nursingdiabetics.com/research/

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Retinopathy:
http://www.nursingdiabetics.com/retinopathy/

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Symptoms of diabetes:
http://www.nursingdiabetics.com/symptoms/

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Traveling and diabetes:
http://www.nursingdiabetics.com/traveling/

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Treatment of Diabetes:
http://www.nursingdiabetics.com/diabetestx/

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Type 1 diabetes/ IDDM:
http://www.nursingdiabetics.com/type1/

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Type 2 diabetes/ NIDDM:
http://www.nursingdiabetics.com/type2/

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Ulcer (diabetic ulcer):
http://www.nursingdiabetics.com/ulcer/

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Women and diabetes:
http://www.nursingdiabetics.com/women/

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Diabetic Medications:
http://www.nursingdiabetics.com/medications/

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Last updated by Andrew Lopez, RN on Wednesday, September 29, 2010


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