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Definition of Diabetes Insipidus:hometown:"DI is defined as a condition in which urine is not concentrated (urine is dilute or water-like). Concentration of urine in normally functioning individuals is the consequence of secretion of antidiuretic hormone (ADH) by the posterior pituitary gland in the brain, and a corresponding reaction by receptors on the kidneys. ADH tells the kidneys how much water to keep in the body and how much water to eliminate as urine."
http://hometown.aol.com/ruudh/dipage1.htm
Diabetes Insipidus-a comprehensive look at this disorder:MEMS:"If you are treated for central diabetes insipidus, the condition is usually corrected by giving synthetic vasopressin. It is administered by placing some in a small plastic tube and gently blowing the liquid into the nostril where it is readily absorbed by the tissue of the nose lining. It can also be taken orally, but the dose required is higher. If you have nephrogenic diabetes insipidus, water pills (thiazide diuretics) may be pre-scribed by your doctor. You may be confused as to why you need to take diuretics for this disorder. Thiazide diuretics have been shown to stimulate the production of a hormone that helps your body retain salt. This added amount of salt keeps you from losing too much wate"
http://www.geocities.com/Tokyo/5830/diabetes_insipidus.htm
What is diabetes insipidus-signs and symptoms, treatments, causes:Methodist Health:"The following are the most common symptoms of diabetes insipidus. However, each individual may experience symptoms differently. Symptoms may include:
excessive thirst excessive urine production dehydration The symptoms of diabetes insipidus may resemble other conditions or medical problems. Always consult your physician for a diagnosis."
http://www.methodisthealth.com/endocrin/diabins.htm
diabetes insipidus another comprehensive review:Thomas Jefferson University Hospitol:"Diabetes insipidus can be caused by several conditions, including the following:
malfunctioning hypothalamus
malfunctioning pituitary gland
damage to hypothalamus or pituitary gland during surgery
brain injury
tumor
tuberculosis
blockage in the arteries leading to the brain
encephalitis
meningitis
sarcoidosis (a rare inflammation of the lymph nodes and other tissues throughout the body)"
http://www.jeffersonhospital.org/e3front.dll?durki=4866
Diabetes Insipidus-overview of the disease:UNIVERSITY OF MARYLAND MEDICINE:"Treating diabetes insipidus depends on what is causing the disease. Treating the cause usually treats the diabetes insipidus. Specific treatment for diabetes insipidus will be determined by your physician based on:
your overall health and medical history
extent of the disease
your tolerance for specific medications, procedures, or therapies
expectations for the course of the disease
your opinion or preference
Treatment may include modified antidiuretic hormone drugs or drugs to stimulate the production of the antidiuretic hormone"
http://www.umm.edu/endocrin/diabins.htm
Diabetes Insipidus General Illness Information:rx med:"Medications:
Vasopressin or desmopressin acetate, modified synthetic forms of antidiuretic hormone, may be taken as a nasal spray several times a day, to maintain a normal urine output. However, taking too much of this medication can cause fluid retention and swelling and other problems.
Sometimes diabetes insipidus can be controlled with drugs that stimulate production of antidiuretic hormone such as chlorpropamide, carbamazepine, clofibrate."
http://www.rxmed.com/rxmed/b.main/b1.illness/b1.1.illnesses/diabetes%20insipidus.htm
Diabetes Insipidus facts and statistics:NDI foundation:"There are three types of inherited NDI:
1. X-linked NDI is the most common type of inherited NDI. It affects males more often than females. Males are certain to be seriously affected by NDI if they inherit the gene, whereas females are usually affected mildly or not at all. Rarely, girls may be affected as severely as boys. Females who carry this gene, whether or not they show symptoms, will pass it on to their daughters and their sons 50% of the time.
2. Autosomal recessive NDI is a much rarer type of inherited NDI. It affects males and females equally. For a child to have the disease, both parents must carry this gene. Parents who are both carriers of this form of NDI have a 25% chance with each pregnancy of having another affected child.
3. Autosomal dominant NDI is an extremely rare type of NDI. It affects both males and females. For a child to inherit this type of NDI, only one parent need carry the gene."
http://www.ndif.org/facts.html
Types of diabetes insipidus
:diabetesinsipidus.maxinter.net:"Neurogenic, also known as central, hypothalamic, pituitary or neurohypophyseal is caused by a deficiency of the antidiuretic hormone, vasopressin. Nephrogenic, also known as vasopressin-resistant is caused by insensitivity of the kidneys to the effect of the antidiuretic hormone, vasopressin. More information about Nephrogenic DI can be found at http://www.ndif.org. Gestagenic, also known as gestational is also caused by a deficiency of the antidiuretic hormone, vasopressin, that occurs only during pregnancy. Dipsogenic, a form of primary polydipsia is caused by abnormal thirst and the excessive intake of water or other liquids."
http://diabetesinsipidus.maxinter.net/
What causes diabetes insipidus?:American Academy of Family Physicians:"Two things cause diabetes insipidus. In some people, a part of the brain (called the hypothalamus) doesn't make enough antidiuretic hormone (called ADH), which your body needs to work right. In other people, the kidneys don't work with this hormone the way they should. Most people with diabetes insipidus get it after an injury to the head or after brain surgery. Some people with diabetes insipidus have a brain tumor. Sometimes it runs in families. Some medicines, like lithium, can cause it. About 25% of the time, doctors can't find any reason for it."
http://familydoctor.org/handouts/048.html
Diabetes Insipidus:Keep kids healthy:"Arginine vasopressin is normally produced in the hypothalamus, and so there can be a decrease in the its production caused by any condition that disrupts the hypothalamus, including brain tumors and head trauma, and some inherited conditions (septo-optic dysplasia). Nephrogenic DI can either be inherited or it can be a side effect of some medications, including Lithium, and some chronic conditions, such as sickle cell anemia, pyelonephritis, and urinary tract obstructions."
http://www.keepkidshealthy.com/welcome/conditions/diabetes_insipidus.html
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