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Glynase (Glyburide, Micronase)

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Glynase (glyburide, Micronase) description:rxlist:"Micronase Tablets (Standard Glyburide): Micronase tablets contain glyburide, which is an oral blood-glucose-lowering drug of the sulfonylurea class. Glyburide is a white, crystalline compound, formulated as Micronase tablets of 1.25, 2.5, and 5 mg strengths for oral administration. Inactive Ingredients: Colloidal silicon dioxide, dibasic calcium phosphate, magnesium stearate, microcrystalline cellulose, sodium alginate, talc. In addition, the 2.5 mg contains aluminum oxide and FD&C red no. 40 and the 5 mg contains aluminum oxide and FD&C blue no. 1."
http://www.rxlist.com/cgi/generic/glymic.htm

Glynase (glyburide, Micronase) Why is this drug prescribed?:gettingwell.com:"Micronase is an oral antidiabetic medication used to treat type 2 diabetes, the kind that occurs when the body either does not make enough insulin or fails to use insulin properly. Insulin transfers sugar from the bloodstream to the body's cells, where it is then used for energy. There are two forms of diabetes: type 1 and type 2. Type 1 diabetes results from a complete shutdown of normal insulin production and usually requires insulin injections for life, while type 2 diabetes can usually be treated by dietary changes, exercise, and/or oral antidiabetic medications such as Micronase. This medication controls diabetes by stimulating the pancreas to produce more insulin and by helping insulin to work better. Type 2 diabetics may need insulin injections, sometimes only temporarily during stressful periods such as illness, or on a long-term basis if an oral antidiabetic medication fails to control blood sugar. Micronase can be used alone or along with a drug called metformin (Glucophage) if diet plus either drug alone fails to control sugar levels"
http://www.gettingwell.com/drug_info/rxdrugprofiles/drugs/MIC1264.shtml

What is the most important information I should know about Glynase (glyburide, Micronase):ahealthyme.com:"Know the signs and symptoms of low blood sugar (hypoglycemia), which include headache, drowsiness, weakness, dizziness, fast heartbeat, sweating, tremor, and nausea. Carry a piece of hard candy or glucose tablets with you to treat episodes of low blood sugar. Follow your diet, medication, and exercise routines very closely. Changing any of them can affect your blood sugar levels. Do not increase the dose of this medicine without first talking to your doctor. Avoid alcohol. It lowers blood sugar and may interfere with your diabetes treatment"
http://www.ahealthyme.com/topic/topic100589974

Precautions when taking Glynase (glyburide, Micronase):healthtrust.com:"Wear disease medical alert identification for diabetes. If you are 80 years of age or older, you may be more sensitive to low blood sugars. Avoid alcohol intake (includes wine, beer, and liquor). Keep hard candies, liquid glucose, or milk on hand for low blood sugars. Do not drive if blood sugar has been low. There is a greater risk of an accident. Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved. Tell healthcare provider if you are pregnant or plan on getting pregnant. Tell healthcare provider if you are breast-feeding"
http://www.healthtrust.com/intmed/Access2Cons2/ConsDrugs/Glyburidecd.shtml

Glynase (glyburide, Micronase) side effects:drugs.com:"Stop taking glyburide and seek emergency medical attention or call your doctor immediately if you experience any of the following serious side effects: an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); or low blood sugar (drowsiness, headache, nausea, tremor, dizziness, unconsciousness). Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome."
http://www.drugs.com/xq/cfm/pageID_0/htm_D00248A3.htm/bn_Glynase/qx/index.htm

Glynase (glyburide, Micronase) who is it for?:drugdigest:"Glyburide is used to treat Type 2 (noninsulin-dependent) diabetes (formerly "adult-onset"), particularly in people whose diabetes cannot be controlled by diet alone. Glyburide is not used to treat Type 1 (insulin-dependent) diabetes (formerly "juvenile-onset"). This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information"
http://www.drugdigest.org/DD/DVH/Uses/0,3915,300|Glynase,00.html

What are the precautions when taking Glynase (glyburide, Micronase):usadrug.com:"Wear disease medical alert identification for diabetes. If you are 80 years of age or older, you may be more sensitive to low blood sugars. Avoid alcohol intake (includes wine, beer, and liquor). Keep hard candies, liquid glucose, or milk on hand for low blood sugars. Do not drive if blood sugar has been low. There is a greater risk of an accident. Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved. Tell healthcare provider if you are pregnant or plan on getting pregnant. Tell healthcare provider if you are breast-feeding"
http://www.usadrug.com/IMCAccess/ConsDrugs/Glyburidecd.shtml

Side effects and interactions of Glynase (glyburide, Micronase):healthcentral.com:"A number of compounds may interact with DiaBeta. Alcohol should be avoided if you are on this drug, as it could cause low blood sugar. Other drugs that might lead to drops in blood sugar include large doses of aspirin, the ulcer drugs Tagamet and Zantac, the cholesterol medicine Lopid and the MAO inhibitor antidepressants Marplan and Nardil. Be aware that a magnesium-based antacid like Maalox or laxative like Milk of Magnesia could boost the power of DiaBeta and lead to unexpectedly low blood sugar levels. Many blood pressure pills and heart medicines may also interact with DiaBeta."
http://www.healthcentral.com/peoplespharmacy/PPDrugFullText_SideEffBrand.cfm?ID=22&brandname=Glynase

Glynase (glyburide, Micronase)uses and instructions:ElizJack@IntNet.Net:"This medication is used in the treatment of non-insulin dependent diabetes. It must be used in conjunction with proper diet and exercise to help decrease blood sugar levels. How to take this medication: May be taken with food or milk if stomach upset occurs. Take this medication at the same time(s) each day in order to maintain a constant blood level. Monitor blood glucose levels daily while taking this medication. You may need to be switched to insulin therapy if you develop a severe infection, diabetic coma or undergo major surgery."
http://members.aol.com/lowcarbs/diabetes/meds/glymic.htm

Glynase (glyburide, Micronase) dosage:nursespdr:"Tablets, Nonmicronized (DiaBeta/Micronase) Diabetes. Adults, initial: 2.5-5 mg/day given with breakfast (or the first main meal); then, increase by 2.5 mg at weekly intervals to achieve the desired response. Maintenance: 1.25-20 mg/day. Clients sensitive to sulfonylureas should start with 1.25 mg/day. Tablets, Micronized (Glynase PresTab) Diabetes. Adults, initial: 1.5-3 mg/day given with breakfast (or the first main meal). Those sensitive to sulfonylureas should start with 0.75 mg/day. Increase by no more than 1.5 mg at weekly intervals to achieve the desired response. Maintenance: 0.75-12 (maximum) mg/day."
http://www.nursespdr.com/members/database/ndrhtml/glyburide.html



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Last updated by Andrew Lopez, RN on Tuesday, April 13, 2010


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