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Tolinase (Tolazamide)

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Tolinase (Tolazamide) dosage information:nursespdr:"Tablets Diabetes. Adults, initial: 100 mg/day if fasting blood sugar is less than 200 mg/100 mL, or 250 mg/day if fasting blood sugar is greater than 200 mg/100 mL. Adjust dose to response, not to exceed 1 g/day; adjust dosage in increments of 100-250 mg at weekly intervals based on client response. If more than 500 mg/day is required, give in two divided doses, usually before the morning and evening meals. Maintenance, average: 250-500 mg/day. Elderly, malnourished, underweight clients or those not eating properly: 100 mg once daily with breakfast, adjusting dose by increments of 50 mg/day each week. Doses greater than 1 g/day will probably not improve control."
http://www.nursespdr.com/members/database/ndrhtml/tolazamide.html

The most important information I should know about Tolinase (Tolazamide):health.msn.com:"Treatment with tolazamide may increase the risk of death from cardiovascular disease compared to treatment of diabetes with diet alone or diet plus insulin. Discuss with your doctor the risks and benefits of treatment with tolazamide. Know the signs and symptoms of low blood sugar (hypoglycemia), which include headache, drowsiness, weakness, dizziness, fast heartbeat, sweating, tremor, and nausea. Carry a piece of hard candy or glucose tablets with you to treat episodes of low blood sugar. Follow your diet, medication, and exercise routines closely. Changing any of them can affect blood sugar levels. Do not change your dose of tolazamide without first talking to your doctor. Avoid alcohol. It lowers blood sugar and may interfere with your diabetes treatment."
http://content.health.msn.com/drug_article/article/4046.2193?bn=Tolinase

Tolinase (Tolazamide) Why is this medication prescribed? :medlineplus:"Tolazamide is used to treat type II (noninsulin-dependent) diabetes (formerly 'adult-onset'), particularly in people whose diabetes cannot be controlled by diet alone. Tolazamide lowers blood sugar by stimulating the pancreas to secrete insulin and helping the body use insulin efficiently. The pancreas must produce insulin for this medication to work. Tolazamide is not used to treat type I(insulin-dependent) diabetes (formerly 'juvenile-onset'). This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information"
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682482.html

Precautions when taking Tolinase (Tolazamide):healthtrust:"Wear disease medical alert identification for diabetes. If you are 80 years of age or older, you may be more sensitive to low blood sugars. Keep hard candies, liquid glucose, or milk on hand for low blood sugars. Do not drive if blood sugar has been low. There is a greater risk of an accident. Avoid alcohol intake (includes wine, beer, and liquor). Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved. Tell healthcare provider if you are pregnant or plan on getting pregnant. Tell healthcare provider if you are breast-feeding"
http://www.healthtrust.com/intmed/Access2Cons2/ConsDrugs/Tolazamidecd.shtml

Who shouldn't take Tolinase (Tolazamide)?:drugs.com:"Before taking this medication, tell your doctor if you have kidney or liver disease; have thyroid disease; have Type 1 diabetes mellitus (insulin-dependent diabetes); have a serious infection, illness, or injury; or need surgery. You may need a lower dose or special monitoring during treatment if you have any of the conditions listed above. Tolazamide is in the FDA pregnancy category D. This means that it is known to harm an unborn baby. Insulin is usually the drug of choice for controlling diabetes during pregnancy. Do not take tolazamide without first talking to your doctor if you are pregnant. It is not known whether tolazamide passes into breast milk. Do not take tolazamide without first talking to your doctor if you are breast-feeding a baby."
http://www.drugs.com/xq/cfm/pageID_0/htm_D00393A1.htm/bn_Tolinase/qx/index.htm

Tolinase (Tolazamide) side effects:ElizJack@IntNet.Net:"Headache, stomach upset, loss of appetite, nausea, diarrhea or vomiting may occur as your body adjusts to the medication. Inform your doctor if you develop itchy skin, dark urine, fever, sore throat, swelling of the hands or feet or unusual bleeding or bruising while taking this medication. This medication can cause low blood sugar (hypoglycemia). The symptoms include chills, cold sweat, shaking, rapid heart rate, weakness, headache, fainting. If you experience these symptoms, eat a quick source of sugar such as table sugar, orange juice, honey, non-diet soda. Tell your doctor about the reaction. To help prevent hypoglycemia, eat meals on a regular schedule and do not skip meals. Symptoms of high blood sugar (hyperglycemia) include confusion, drowsiness, flushing, rapid breathing, or fruity breath odor. If these symptoms occur, contact your doctor. This medication can increase sensitivity to sunlight"
http://members.aol.com/lowcarbs/diabetes/meds/tolaz.htm

What other drugs will affect Tolinase (Tolazamide):rxlist:"Many other medicines may increase or decrease the effects of tolazamide or affect your condition. Before taking tolazamide, tell your doctor if you are taking any of the following medicines: aspirin or another salicylate such as magnesium/choline salicylate (Trilisate), salsalate (Disalcid, others), choline salicylate (Arthropan), magnesium salicylate (Magan), or bismuth subsalicylate (Pepto-Bismol); a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Advil, Nuprin, others), ketoprofen (Orudis, Orudis KT, Oruvail), diclofenac (Voltaren, Cataflam), etodolac (Lodine), indomethacin (Indocin), nabumetone (Relafen), oxaprozin (Daypro), naproxen (Anaprox, Naprosyn, Aleve), and others; a sulfa-based drug such as sulfamethoxazole-trimethoprim (Bactrim, Septra), sulfisoxazole (Gantrisin), or sulfasalazine (Azulfidine); a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil); a beta-blocker such as propranolol (Inderal), atenolol (Tenormin), acebutolol (Sectral), metoprolol (Lopressor), and others; a diuretic (water pill) such as hydrochlorothiazide (HCTZ, Hydrodiuril), chlorothiazide (Diuril), and others;"
http://www.rxlist.com/frame/display.cgi?drug=TOLINASE




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